This study evaluated the economic viability and growth performance of Clarias gariepinus juveniles fed exclusively on three locally formulated diets under a semi-intensive culture system. A total of 150 juveniles (15.8 ± 0.3 g) were distributed into three treatments (D₁ = Maize-Soybean, D₂ = Maize-Groundnut, D₃ = Maize-Bambara), each with 50 fish. Diets were formulated to contain similar crude protein levels and fed twice daily for 12 weeks. Feed cost, feed conversion ratio (FCR), and benefit-cost ratio (BCR) were determined. The results revealed that D₁ had the highest mean final weight (168.25 g), followed by D₂ (145.40 g) and D₃ (136.20 g). Total feed consumed per fish was 185 g (D₁), 178 g (D₂), and 174 g (D₃). Feed costs per fish were ₦88.80, ₦78.32, and ₦74.82 for D₁, D₂, and D₃, respectively. With a market price of ₦3,000/kg and juvenile cost of ₦120, revenue per fish was ₦504.75, ₦436.20, and ₦408.60 for D₁, D₂, and D₃, respectively. Corresponding profits per fish were ₦295.95, ₦237.88, and ₦213.78, with BCR values of 1.42, 1.20, and 1.10, respectively. The results indicate that although all diets were profitable (BCR > 1), maize-soybean-based feed yielded the highest economic returns.