This study explores the acceptance of virtual learning among student nurses at Lagos State College of Nursing (LASCON). Specifically, it examines students‘ knowledge, perception, and acceptance levels regarding the use of virtual learning platforms. A descriptive survey design was employed, with a sample of 133 Basic Nursing students. Data were collected using a structured questionnaire and analyzed using frequency tables, percentages, and correlation analysis. Findings indicate that respondents demonstrated a high level of knowledge and a generally positive perception toward virtual learning. Furthermore, most students showed a strong level of acceptance, although a minority reported lower acceptance. The study concludes that while student nurses at LASCON possess good knowledge of virtual learning, this does not significantly influence their perception. Overall, the results highlight a favorable outlook toward the adoption of virtual learning among the students.